This continues a series of articles that looks at the science behind the health-related benefits of high-quality Extra Virgin Olive Oil like Morocco Gold. Extra Virgin Olive Oil is probably the most extensively researched foodstuff on the planet and the health benefits are evidence based. Thanks to the recent spotlight on the Mediterranean Diet, extensive research has been done on the phytonutrient composition of olive oil. What has been discovered is an extensive list of phytonutrients; one of the most praised is its polyphenols. The amount of polyphenols found in extra virgin olive oil is truly amazing! These have positive anti-inflammatory properites.
Anti-Inflammatory Benefits of Extra Virgin Olive Oil
Phenols and polyphenols serve as the core substances that give Extra Virgin Olive Oil its unique anti-inflammatory properties. Researchers have determined that small amounts of Extra Virgin Olive Oil, as low as one tablespoon per day, can lower inflammatory signalling in our body, including levels of interleukin-6 (IL-6) and tumour necrosis factor alpha (TNF-alpha).
Interestingly, in Mediterranean-type diets that include daily intake of Extra Virgin Olive Oil, not only is there less production of signalling molecules like TNF-alpha, but there is also less activity by the cell receptors for these pro-inflammatory molecules. (This decreased receptor activity has been shown for tumour necrosis factor receptor 60 (TNFR 60) and tumour necrosis factor receptor 80 (TNFR 80). Levels of C-reactive protein (CRP) have also been show to decrease with daily intake of Extra Virgin Olive Oil.
In addition, scientists have shown that individuals who regularly consume Extra Virgin Olive Oil have reduced activity of their pro-inflammatory cyclo-oxygenase 1 (COX-1) and cyclo-oxygenase 2 (COX-2) enzymes, as well as reduced levels of related molecules including thromboxane B2 and leukotriene B4. Two molecules that are known to increase during inflammatory disease processes, vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule 1 (ICAM-1), have also been shown to decrease in amount following intake of Extra Virgin Olive Oil.
In this anti-inflammatory context, it is also worth noting that oxidative stress, a process that often parallels the process of chronic inflammation, is reduced by regular consumption of Extra Virgin Olive Oil. One common blood marker used to monitor oxidative stress is the formation of substances called F2-isoprostanes, and studies have shown 10-15% lower levels of this blood marker following Extra Virgin Olive Oil intake.
Importantly, the anti-inflammatory benefits of Extra Virgin Olive Oil do not depend on large levels of intake. In most studies, these benefits become statistically significant with as little as one tablespoon of Extra Virgin Olive Oil per day.
The anti-inflammatory benefits of Extra Virgin Olive Oil also appear to increase with daily intake above this level. An average daily Extra Virgin Olive Oil amount of 2 tablespoons per day is enough to provide strong anti-inflammatory benefits.
What is Inflammation?
Inflammation is a process that protects the body from infection and foreign substances, such as bacteria and viruses. Inflammation helps the body by producing white blood cells and other substances. Sometimes, the immune system triggers an inflammatory response inappropriately. This is the case with autoimmune diseases. The body compensates by attacking its own healthy tissues, acting as if they are infected or abnormal.
When the inflammation process starts, chemicals in the white blood cells are released into the blood and the affected tissues to protect the body. The chemicals increase blood flow to the infected or injured body areas, causing redness and warmth in those locations. These chemicals may also cause leaking of fluids into tissues, resulting in swelling. This protective process will also stimulate nerves and tissues, causing pain.
Inflammation is classified as either acute or chronic. Acute inflammation is short-term, while chronic inflammation is long-lasting and even destructive.
Acute inflammation is a healthy and necessary function that helps the body to attack bacteria and other foreign substances anywhere in the body. Once the body has healed, inflammation subsides.
Examples of conditions that cause acute inflammation include:
- Acute bronchitis, which causes inflammation of the airways that carry air to the lungs.
- An infected ingrown toenail.
- A sore throat related to the flu.
- Skin cuts and scratches.
- Dermatitis, which describes multiple skin conditions including eczema, which causes red, itchy inflamed rashes in areas where the skin flexes (such as inside the elbows and behind the knees).
- Sinusitis, which can cause short-term inflammation in the membranes of the nose and surrounding sinuses (usually the result of a viral infection)
- physical trauma.
Chronic inflammation, on the other hand, may continue to attack healthy areas if it doesn’t turn off. It can occur anywhere in the body and may trigger any number of chronic diseases, depending on the area of the body affected.
Examples of conditions that cause chronic inflammation include:
- Inflammatory arthritis, which covers a group of conditions distinguished by inflammation of joints and tissues (including rheumatoid arthritis, lupus, and psoriatic arthritis).
- Asthma, which causes inflammation of the air passages that carry oxygen to the lungs. Inflammation causes these airways to become narrow and breathing to become difficult.
- Periodontitis, which causes inflammation of gums and other supporting teeth structures. It is caused by bacteria triggered by local inflammation.
- Inflammatory bowel disease (IBD). IBD refers to Crohn’s disease and ulcerative colitis. Both these conditions cause chronic inflammation in the gastrointestinal (GI) tract that eventually causes damage to the GI tract.
5 Cardinal Signs of Inflammation : Pain, Heat, Redness, Swelling, and Loss of Function
Interestingly, inflammation is a biological process that your body uses to help protect you. It is important to note, however, that not all five cardinal signs are present in every instance of inflammation. Moreover, the inflammatory process could be silent and not cause noticeable symptoms.
A cardinal sign is a major symptom that doctors utilize to make a diagnosis. In the case of inflammation, there are five cardinal signs that characterize the condition: pain, heat, redness, swelling, and loss of function.
Doctors and researchers sometimes refer to the five cardinal signs:Dolor (pain).
Functio laesa (loss of function).
Inflammation can cause pain in joints and muscles. When inflammation is chronic, a person will experience high levels of pain sensitivity and stiffness. The inflamed areas may be sensitive to touch.
With both acute and chronic inflammation, pain is the result of inflammatory chemicals that stimulate nerve endings, causing the affected areas to feel more sensitive.
When inflamed areas of the body feel warm, it is because there is more blood flow in those areas. People with arthritic conditions may have inflamed joints that feel warm to the touch. The skin around those joints, however, may not have the same warmth. Whole-body inflammation may cause fevers as a result of the inflammatory response when someone has an illness or infection.
Inflamed areas of the body may appear red in color. This is because blood vessels of inflamed areas are filled with more blood than usual.
Swelling is common when a part of the body is inflamed. It is the result of fluid accumulating in tissues either throughout the body or in the specific affected area. Swelling can occur without inflammation, especially with injuries.
Loss of Function
Inflammation may cause loss of function, related to both injury and illness. For example, an inflamed joint cannot be moved properly, or it can make it difficult to breathe due to a respiratory infection.
Additional Signs and Complications
When inflammation is severe, it may cause additional signs and symptoms. This may include a general feeling of sickness and exhaustion. Inflammation due to illness may have dangerous complications, including a condition called sepsis. Sepsis occurs when the body’s immune system overwhelmingly responds to a serious infection, which leads to generalized, life-threatening tissue damage.
Inflammation is a necessary part of the healing process and usually nothing to worry about. But when inflammation is chronic, it can be a serious health problem. Anyone experiencing ongoing inflammation should talk to their doctor about determining the source of inflammation and getting appropriate treatment to avoid any serious complications.